Advanced paternity: New study reveals risks to pregnancy and baby

Advanced paternity: New study reveals risks to pregnancy and baby

According to the American Society of Reproductive Medicine (ASRM), an advanced paternal age is linked to a greater risk of autism, schizophrenia and some genetic diseasesalthough the mechanisms behind these risks are not yet clear.

A European study conducted in Clinics of Italy and Spain concluded that The father’s age directly influences the success of fertility treatments. According to the investigation, the older men of 45 years They present a higher risk of miscarriage and lower rate of living birthseven with young ovules.

The investigation, presented at the Congress of the European Society for Human Reproduction and Embryology (Eshre), analyzed 1.712 Assisted reproduction cycles made in Clinics of Italy and Spain. The ovules came from young women, with an average of 26 years, while the receivers were on average 43.3 years. The men were divided into two groups: Children and over 45 years.

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Study presented at the European Reproduction Congress.

Study presented at the European Reproduction Congress.

The results showed a significant difference between both groups. In cases where the father was over 45, the abortion rate reached the 23.8%in front of the 16.3% In younger men. In addition, the living birth rate also descended: 41% to 35.1% In older men.

Baby health risks associated with late fatherhood

While traditionally, the focus is almost exclusively in the maternal age, this evidence shows that The male factor is also decisive. According to the American Society of Reproductive Medicine (ASRM), an advanced paternal age is linked to a greater risk of autism, schizophrenia and some genetic diseasesalthough the mechanisms behind these risks are not yet clear.

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Older parents have more abortions and less births.

Older parents have more abortions and less births.

“For a long time we assume that, if the ovules were young, everything else did not matter, but it is not because there is a male part that It also influences “explained the doctor María Cristina Guglielmoclinical and responsible for the study.

Why this finding changes the clinical perspective

From the medical point of view, the use of Donated ovules allows isolate The female component, which makes any difference in the results can be attributed with greater precision to the male factor. This allows you to refine the analysis and better understand how the age of man influences embryonic development and pregnancy.

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Advanced paternal age linked to genetic risks.

Advanced paternal age linked to genetic risks.

Guglielmo clarified that the objective of the study is not to generate alarm: “It is not guilty or alarm, but Understand what factors can condition the results and how we can better accompany these processes. ”

Fertility is a shared path. And science begins to make it clear: The father’s age also counts.

Source: Ambito

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