Ozempic & Co.
Medicines against obesity: So quickly you increase again
Ozempic, Wegovy and Mounjaro are celebrated: Such medication let pounds melt. But how long does the effect last? Researchers have analyzed data on some active ingredients.
Medicines that make it easier to lose weight are currently a great promise of salvation. But after stopping some active ingredients, according to a study, it quickly goes back in the other direction.
The people who received the active ingredients decreased considerably during the therapy – which could still take a small extent for a few weeks after stopping the medication, as. But from week eight after the end of the therapy, the researchers followed a significant increase in weight that endures for many weeks.
Significant increase after stopping funds such as Ozempic
According to the medication and lifestyle change, the extent of weight gain is different, but there is a significant trend towards weight gain after taking medication.
According to Stephan Martin, chief physician for diabetology and director of the West German Diabetes and Health Center of the Association of Catholic Clinics in Düsseldorf, they confirm existing knowledge. Some of the medication manufacturers would also have proven this by randomized studies, reports expert, who was not involved in the evaluated studies. For example, subjects received the active ingredients for ten weeks, then one part only a placebo. This group “has then continuously increased again,” reports Martin.
In the current study, also in the current study, the researchers from Beijing, for example, refer to an investigation that people who had completed a 36-week treatment with the Arzneistoff Tirepatid (GLP-1-RA) have increased around half of the weight previously lost one year after the changeover to a placebo.
Examined effects of several active ingredients
For the meta-analysis that has now been published, the results of eleven independent studies from all over the world were summarized-including the drug orlistat, the combinations Naltrexon/BUPROPION and phenter/topiramate as well as the active ingredient group GLP-1 receptor agonists. The data comes from a total of 1,574 people in treatment and 893 in control groups.
GLP-1 receptor agonists (GLP-1-RA) are included in the sought-after medication Wegovy and Ozempic, for example. They are approved in Germany against diabetes 2 and some cases of obesity-and they are known as lifestyle preparations for a slim figure. The active ingredients that are injected regularly extend the length of stay of food in the digestive tract and thus increase the feeling of satiety. The side effects include gastrointestinal complaints.
One aspect in the study is noticeable: Anyone who initially had a strong weight loss in therapy is increasing again after the data- even if the patients took part in a program to change their lifestyle, such as eating and movement behavior.
“That doesn’t surprise me,” says Anja Hilbert, professor of behavioral medicine at the University Hospital Leipzig. For example, similar people experienced people who comply with a strongly calorie -reduced diet – after their end, they also increase more than people who would go through a moderate calorie restriction. However, the expert restricts that there were only a few participants for this aspect of the examination.
“You need this therapy permanently”
“The results of the study actually suggest that a long -term, perhaps even lifelong intake could be necessary to stabilize weight,” Hilbert draws a conclusion. Diabetologist Martin also emphasizes: “It is permanent therapy.” Anyone who believes that he can lose weight with this therapy and then the world is okay, the crazy. “You need this therapy permanently.”
However, figures from the United States allowed the fear that many people are not aware of it or would be accepted by them, explains Martin. According to investigations, two thirds of the people treated against obesity, mostly self -paying, had stopped again in the course of a year. “We do not know why: maybe it will be too expensive, maybe you have lost enough weight and believe that this is now going on,” says the chief physician for diabetology, who pleads for more prevention instead of treatment of the consequences.
Do you want to lose weight? You should avoid these five nutritional errors
Losing weight healthy: You should avoid these five nutritional errors
Error 1: Salads are always a healthy choice
“Salad” is a very stretchy term in Germany. Salatry cups in supermarkets or restaurants often contain cold pasta dishes with greasy sauces or finely chopped sausages with onion pieces. This is anything but healthy and has little in common with the basic idea of a salad.
Some salads such as the so -called “Caesar Salad” look fresh, green and healthy, but also provide plenty of calories and hidden fats. Caution should be exercised especially in white dressing sauces: they usually contain a lot of oil and/or mayonnaise and can transform a supposedly healthy portion of salad into a lush main course. Even croutons, bacon strips or parmesan plane screw the calorie content of a salad up properly.
Tip: Compare the nutritional table from lettuce sauces. Balsamic varying is usually easier than white dressings. It is even better if you mix the dressing yourself – for example from fresh lemon juice, olive oil, some mustard, honey, salt and pepper. You should use toppings sparingly.
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The costs are also an issue in Germany: “Treatment with GLP-1-RA costs a few hundred euros per month, about 23 percent of our population have obesity,” explains Hilbert, who also promotes overweight prevention. “If you calculate what it would cost to give all those affected permanently access to these medication, it can be seen how difficult it would be to finance.”
Dpa
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Source: Stern
I’m Caroline, a journalist and author for 24 Hours Worlds. I specialize in health-related news and stories, bringing real-world impact to readers across the globe. With my experience in journalism and writing in both print and online formats, I strive to provide reliable information that resonates with audiences from all walks of life.
