For its part, until last week, the United Kingdom has identified a total of 163 children under the age of 16 with this hepatitis. Of these cases, 11 children have required a liver transplant.
Outside the European Union (EU) and the United Kingdom, there are at least 181 cases of acute hepatitis in children in Argentina (8), Brazil (16), Canada (7), Costa Rica (2), Indonesia (15), Israel (12), Japan (7), Panama (1), Palestine (1), Serbia (1), Singapore (1), South Korea (1), and the United States (at least 109).
Thus, the total number of reported cases worldwide is approximately 450, including 11 deaths in Indonesia (5), Palestine (1), and the United States (5). The death of an eight-year-old boy in Palestine is still under investigation as “it is currently unclear whether this is the same boy who was killed the previous week.”
The ECDC also assures that “it is still not clear if the cases identified after the alert are part of a true increase compared to the usual rate of hepatitis of unknown etiology in children.”
Meanwhile, both the etiology and the pathogenic mechanisms of the disease “remain under investigation.” “A possible association with current adenovirus infection has been found in the UK cases in particular, but other hypotheses and potential cofactors are being investigated. Most cases continue to be reported as sporadic unrelated cases.”remember the European center.
Source: Ambito
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