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However, those affected also experience a second problem: they often suffer from a heart attack or a stroke at an early stage. The risk has been associated in particular with vascular calcification (atherosclerosis), which occurs more quickly due to inflammatory processes. However, Italian scientists have now proven a malfunction of the heart’s small blood vessels as a possible cause. Dermatologist Stefano Piaserico from the University of Padua in Italy speaks of “coronary microvascular dysfunction.” Such a malfunction leads to a reduction in the ability of the heart’s blood vessels to dilate accordingly with increased oxygen demand.
Effects on therapy
According to experts, this should have consequences for the treatment itself. A highly effective therapy for the skin disease is likely to lead to a recovery in the function of the heart vessels, the authors wrote. This has already been proven several times using certain biotech drugs.
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Source: Nachrichten
