As indicated by the research filmmakers, vaccines They were applied after surgeries that are carried out to remove the malignant tumor. That is to say, Once cancerthe patient is immunized.
In addition, inoculation injections are scientifically designed to train the immune system of the body a Recognize and remove any cell tumor that may remain. At the time the data were extracted, all patients remained free of cancer.
The word of researchers
Toni Chouirione of the main authors of the study and director of the LANK CENTER For cancer, he explained: “We are very excited about results that show such a positive response in the nine patients with kidney cancer. “
“He habitual treatment for patients With renal cancer it is surgery to remove the tumor, which can be accompanied by immunotherapy with the medication Pmbrolizumabwhich helps reduce the risk of the disease reappearing again, “he explained.
“However, approximately in two thirds of patients can return To emerge and in that case, the treatment options are more limited, “added the specialist.
Then he stressed: “Patients with kidney cancer in stage III or IV They have a high risk of recurrence. The tools we have to reduce that risk are not perfect and we are constantly looking for more. “
How the development of the vaccine continues
As explained, this clinical trial was treated nine patients with renal carcinoma in stages III or IV and another five received the Ipilimumab drug Next to this vaccine.
Vaccines were performed through the Tumor tissue removal During surgery, extracting characteristics of tumor cells that differentiate them from normal cells.
Subsequently, the vaccine was manufactured and the patient was administered in initial doses and other subsequent ones of reinforcement. In some cases they gave themselves local reactions in the place of injection of the vaccine and in others they experienced symptoms similar to those of flualthough no more serious side effects were reported.
This study It started 8 years agobut it was not clear if your approach could work in kidney cancer. Yes ok, It had been shown that it had great potential to be effective against melanoma, A cancer with more mutations than kidney cancer.
It was shown that The vaccine induces an immune response in three weeksmultiplying by 166 the number of T cells, responsible for protecting the body from infections and combating cancer. Besides, These levels remain raised for three years.
Source: Ambito
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