The ANMAT authorized a new drug to treat cancer

The ANMAT authorized a new drug to treat cancer

The National Administration of Drugs, Food and Medical Technology (ANMAT) authorized the use of a new treatment for him bladder cancer locally advanced or metastatic in Argentina. Until now, the therapeutic alternatives to treat it were limited, so it is believed that enfortumab vedotin It could represent a big change.

This medication has a novel mechanism of actionsince it is an antibody that, upon entering the body, binds to the tumor cell and releases the chemotherapywith the objective of delete it.

“He demonstrated great effectiveness in treatment of patients with bladder tumors in advanced stages of the disease, particularly in those who were previously treated with other drugs such as chemotherapy and immunotherapy,” he indicated Federico Loscooncologist at the Uro-Oncology Unit of the Alexander Fleming Institute.

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Globally, the bladder cancer has an incidence of almost 600 thousand new cases and more of 200 thousand deaths annually.

“Until very recently we only had the possibility of treating patients with traditional chemotherapy, which continues to be a very important tool for the treatment of the disease. But in patients where this did not work or the disease worsened later of a treatment period we had nothing“he explained.

“Enfortumab vedotin is a new option that has proven to prolong survival and increase the response of the disease in studies carried out in a large number of patients around the world including studies where they participated patients from Argentina“he described.

Currently, there are research protocols for this medication in both the Italian Hospital and the Fleming, so it is expected that its use in the country be implemented in the next months.

Bladder cancer: what are the risk factors

In the country, the incidence is 3,780 new cases per yearand it is expected that for the 2025 This rate increases to 4,176which would represent a 10.3% increase. At the same time, the estimated number of deaths would amount to 1,823which would imply a 11.2% growth.

According to what is reported by the World Health Organization (WHO)one of the main causes of bladder cancer is smokingresponsible for close to the 50% of cases diagnosed. However, there are other factors less common, such as exposure to chemicals; the intake of contaminated water; or suffer schistosomiasisa common parasitic disease in rural populations of Latin America and Africa.

On the other hand, some research supports a Connection between the infection of human papillomavirus (HPV) and the development of bladder cancer. According to estimates, it is possible that a 17% of cases of bladder tumors are due to some extent to the presence of high-risk HPV serotypes.

According to research, the genetic and hereditary factors could have a bearing on contracting this disease. There is a slight risk trend in the first degree relatives of those who have already been diagnosed with this disease, especially if screening is done before 60 years.

Main symptoms

The bladder cancer symptoms They may vary from one person to another, so it is recommended consult with a professional if one or more of the following is detected:

  • Hematuria (blood in urine)
  • Need to urinate frequently
  • Pain or burning when urinating
  • Feeling like you need to urinate even though your bladder is not full
  • Need to urinate several times during the night

Source: Ambito

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