A study conducted by the Icahn School of Medicine at Mount Sinai revealed that fasting can have negative effects in the fight against infections and can increase the chance of suffering heart diseases.
The research is one of the first to establish the connection between the brain and these immune cells during fasting.
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The research focused on mouse models and is one of the first to show that skipping Eating triggers a response in the brain that negatively affects immune cells. Specialists maintain that the results could lead to a better understanding of how the Chronic fasting can affect the body in the long term.
Researchers sought to better understand how fasting, from one relatively short from a few hours to a more severe fast of 24 hours, affects the immune system. The study consisted of separating two groups of mice: one had breakfast immediately after waking up and the other did not. From this, blood samples were taken when the mice woke up, then four hours later and eight hours later.
When they examined the results there was a clear difference between both groups. Specifically, the researchers saw a difference in the number of monocyteswhich are white blood cells that are produced in the bone marrow and travel throughout the body, where they perform many critical functions, from fighting infections to heart disease and cancer.
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Philip Swirskithe study’s lead author, Ph.D., and director of the Cardiovascular Research Institute at Icahn Mount Sinai, noted that “there is increasing awareness that fasting is healthy and, in fact, there is abundant evidence of the benefits of fasting.” himself” and continued, “Our study offers a caution, as it suggests that fasting may also have a cost that carries a health risk.”
This study is pioneering in identifying the connection between the brain and immune cells called monocytes during fasting. The researchers found that certain areas of the brain regulate the monocyte response during fasting, suggesting that hunger triggers a response of stress in the brain that causes the migration of these white blood cells from the bone marrow into the bloodstream.
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