Why the Dolly sheep, the first cloned mammal, lived only 6 years? This revealed science

Why the Dolly sheep, the first cloned mammal, lived only 6 years? This revealed science

The birth of the first cloned mammal from an adult cell was a before and after in the world of science.

The Dolly sheep was the first cloned mammal From an adult cell, a revolutionary achievement that was achieved in 1996. Anyway, His premature death at 6 years He opened a debate on the limits of cloning.

Dolly’s story is still a reference in research on cloning and aging. His short life drives scientists to improve cloning techniques and better understand the mechanisms that control the longevity of a living being.

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Why did the Dolly sheep died truly

Although the Life expectancy of a sheep It is from 11 to 12 years, Dolly Unfortunately, arthritis developed at 5 and died at 6 Because of ovine pulmonary adenomatosis, a viral disease that causes lung cancer in sheep Sometimes it also causes it in goats. So that he did not sufferhis death occurred by euthanasia.

This common disease in sheep He worsened for his general state of health, what led to investigate If the cloning had accelerated its aging. This led to the scientists They would discover that the telomeres (DNA regions that are at the ends of the chromosomes) of Dolly were shorter than normal For your age. As the donor cell came from a sheep of 6 years, Dolly was born with a “GENETIC AGE” advanced. This suggests that cloning Do not completely restart the biological clock.

The chemical modifications in their DNA, inherited from the donor sheep, could have contributed to its premature deterioration, evidencing that aging does not depend only on genes, but also on how they regulate.

Source: Ambito

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