Image: private
Image: private
Chemical agents change cells and their appearance. With an intelligent image search engine you can predict which chemicals you need to trigger a certain effect, report researchers at the University of Linz. It can also determine which chemicals have caused the cell structure to appear. The study by JKU researchers Ana Sanchez and Elisabeth Rumetshofer from the Institute for Machine Learning was published in the journal “Nature Communications” published.
They developed an intelligent algorithm that uses “Contrastive learning” (Contrastive Learning) biomedical images are associated with the chemicals that shaped them.
Image: private
If you have an active ingredient that changes cells in a certain way, you can use a chemical database to search for other substances that may have a similar effect using the image of the cells. Conversely, you can use the “CLOOME” The bioimage search engine mentioned above can predict possible biological effects for chemical structures whose effect on cells is currently unknown.
“This facilitates the identification of drugs with similar effects, the discovery of new areas of application for existing drugs and the prediction of biochemical effects and properties of new drugs”said Ana Sanchez and Elisabeth Rumetshofer (both University of Linz) in a broadcast: “The search engine therefore has the potential to significantly accelerate drug development.”
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